5-Hydroxytryptophan (5-HTP), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor in the biosynthesis of serotonin and melatonin. As an intermediate in the metabolic pathway from tryptophan to serotonin (5-hydroxytryptamine), 5-HTP readily crosses the blood-brain barrier, making it a highly bioavailable ingredient for supporting neurotransmitter balance. In the body, L-Tryptophan is converted to 5-HTP by the enzyme tryptophan hydroxylase. 5-HTP is then decarboxylated by aromatic amino acid decarboxylase into serotonin. This direct precursor role makes 5-HTP a strategically important active pharmaceutical and nutraceutical ingredient.
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| CAS No. | 4350-09-8 |
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